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Hydrolyzed Collagen

Hydrolyzed Collagen is a modified form of collagen that is easier for the body to digest and absorb. Hydrolyzed collagen is also called HCP, collagen hydrolysate, and purified gelatin. Biologist gave regular collagen and hydrolyzed collagen to mice and exposed them to UV light. The hydrolyzed collagen protected the skin from UV light induced damage better then the regular collagen did. A different set of scientists studied wound healing in dogs. They found that hydrolyzed collagen promoted new skin growth.

Hydrolyzed Collagen and Skin Photoaging
In the first study, researchers investigated how hydrolyzed collagen would affect skin photoaging. Skin photoaging is the damage done to skin by light. The biologists harvested collagen from jellyfish. They hydrolyzed a portion of that collagen so that they had a supply of regular collagen and a supply of hydrolyzed collagen. The researchers gave regular collagen to one group of mice and hydrolyzed collagen to the other group of mice. Then they exposed the mice to UV light.

The researchers examined the mouse skin for signs of damage from the UV light. Both groups of mice had reduced levels of skin damage as a result of the treatments they received. However, the mice that received hydrolyzed collage were better protected than the mice that received regular collagen were. The investigators believed that the regular collagen and the hydrolyzed collagen may have worked as antioxadives to protect the skin and that they help repair the skin's natural ability to produce collagen.

Hydrolyzed Collagen and Skin Growth
In the second study, biologists looked at the effects of topically applied hydrolyzed collagen on new skin growth in dogs. Each dog had two wounds on its trunk. The researchers bandaged one wound on each dog with a simple dressing. These wounds were the control group. They bandaged the other wound on each dog with powdered hydrolyzed collagen and a dressing. These wounds were the experimental group.

The scientists monitored all the wounds as they healed. After 7 days, the wounds that received hydrolyzed collagen had significantly more new skin growth. The researchers attributed this effect to hydrolyzed collagen's ability to bind to water. They believe that the hydrolyzed collagen drew fluids from the body into the wound, which kept the wound cleaner and promoted new skin growth.


Experiments with Hydrolyzed Collagen





Experimental Group





Regular Collagen


Hydrolyzed Collagen

Hydrolyzed Collagen Protected Skin from UV Light Better




Dressing without Hydrolyzed Collagen


Dressing with Hydrolyzed Collagen

Hydrolyzed Collagen Promoted New Skin Growth


Studies on both mice and dogs demonstrated the benefits of hydrolyzed collagen. Mice that received hydrolyze collagen suffered less skin damage from UV light when compared to mice that received regular collagen. A study on dogs revealed that powdered hydrolyzed collagen caused new skin to grow more quickly. These studies suggest that hydrolyzed collagen is good for skin.


1. Effects of Collagen and Collagen Hydrolysate from Jellyfish (Rhopilema esculentum) on Mice Skin Photoaging Induced by UV Irradiation. Journal of Food Science

2. Effects of a Hydrolyzed Collagen Dressing on the Healing of Open Wounds in Dogs. American Journal of Veterinary Research

3. Hydrolyzed Collagen (Hydrolysate). The Free Dictionary