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StriVectin Review

StriVectin™ is a cosmetic topical that delivers niacin (NIA-114) to the skin. Both are trademarks of Klein-Becker. According to the Mayo Clinic, niacin has many health benefits, but it also has side effects. Experts warn against taking products with higher concentrations of  niacin without a doctor's supervision. As such, one may wish to consult a healthcare professional before starting a regiment of StriVectin.

StriVectin Has NIA-114™
The StriVectin website emphasizes that its topical contains NIA-114™, which appears to be a modified niacin. The website  explains that NIA-114™ has a long carbon chain attached to it that allows it to interact with lipids. The outer skin layer is made of lipids and a protein called keratin. This outer layer is waterproof and keeps chemicals out of the deeper layers. The website states that NIA-114™ can penetrate deeper into the skin because it interacts with the lipids in the outer skin layer.

Both topical and oral niacin are prescribed by doctors to treat various medical conditions. It could make sense to take niacin under a doctor's care for certain conditions. Some may argue against applying niacin on the skin for wrinkles without medical supervision for a couple of reasons:

1. A Healthy Diet Has Plenty of Niacin
The Mayo Clinic reports that most people get sufficient niacin from diet alone. It is available in meats, poultry, fish, eggs, dairy products, nuts, and enriched grain products. The body can also produce niacin from tryptophan, an amino acid found in many foods. Niacin from food is transported to the deep layers of the skin through the small blood vessels that populate those layers. There may be no need to resort to advanced chemistry to get nutrients to the deep layers of the skin, because nature has already provided a digestive system and a circulatory system to perform that task.

2. Niacin Can Cause Side Effects
The Mayo Clinic goes on to warm readers that they should not take niacin, even certain niacin supplements, without the supervision of a medical professional. Dosage is important. Niacin supplements and pharmaceuticals have higher dosages of niacin than food does. At these levels, niacin can cause side effects. Flushing of the skin is one possible side effect of niacin supplements. This turns the skin red. Other possible problems include headaches, dizziness and  upset stomach. Certain niacin prescriptions and supplements should not be taken without first consulting a doctor.

Risks of Niacin Supplements
•    Red, Flushed Skin
•    Headaches
•    Upset Stomach
•    Dizziness

StriVectin uses complex chemistry to get niacin past the outer layer of skin. This may be unnecessary, because a healthy diet contains plenty of niacin, and the bloodstream carries niacin from the digestive system to the deep layers of skin. A topical  with niacin, such as StriVectin™, may expose the body to higher than normal levels of this chemical. If in doubt, consult a healthcare professional before using niacin based products, including topicals such as StriVectin.


1. StriVectin. Official Website

2. Simultaneous Determination of Myristyl Nicotinate, Nicotinic Acid, and Nicotinamide in Rabbit Plasma by Liquid Chromatography - Tandem Mass Spectrometry Using Methyl Ethyl Ketone as a Deproteinization Solvent. Centre National de la Recherche Scientifique

3. Niacin (Vitamin B3, Nicotinic Acid), Niacinamide. Mayo Clinic

4. High Cholesterol. Mayo Clinic